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ELIMED: a new hadron therapy concept based on laser driven ion beams
- Source :
- Laser Acceleration of Electrons, Protons, and Ions, Prague; Czech Republic, 15-18 April 2013, info:cnr-pdr/source/autori:Cirrone G.A.P, Margarone D., Maggiore M., Anzalone A., Borghesi M., Jia S.B.d, Bulanov S.S., Bulanov S., Carpinelli M., Cavallaro S., Cutroneo M., Cuttone G., Favetta M., Gammino S., Klimo O., Manti L., Korn G., Malfa G.L., Limpouch J., Musumarra A., Petrovic I., Prokupek J., Psikal J., Ristic-Fira A., Renis M., Romano F.P., Roman F., Schettino G., Schillaci F., Scuderi V., Stancampiano C., Tramontana A., Ter-Avetisyan S., Tomasello B., Torrisi, L. Tudisco S., Velyhan A./congresso_nome:Laser Acceleration of Electrons, Protons, and Ions/congresso_luogo:Prague; Czech Republic/congresso_data:15-18 April 2013/anno:2013/pagina_da:/pagina_a:/intervallo_pagine
- Publication Year :
- 2013
- Publisher :
- SPIE, 2013.
-
Abstract
- Laser accelerated proton beams have been proposed to be used in different research fields. A great interest has risen for the potential replacement of conventional accelerating machines with laser-based accelerators, and in particular for the development of new concepts of more compact and cheaper hadrontherapy centers. In this context the ELIMED (ELI MEDical applications) research project has been launched by INFN-LNS and ASCR-FZU researchers within the pan-European ELI-Beamlines facility framework. The ELIMED project aims to demonstrate the potential clinical applicability of optically accelerated proton beams and to realize a laser-accelerated ion transport beamline for multi-disciplinary user applications. In this framework the eye melanoma, as for instance the uveal melanoma normally treated with 62 MeV proton beams produced by standard accelerators, will be considered as a model system to demonstrate the potential clinical use of laser-driven protons in hadrontherapy, especially because of the limited constraints in terms of proton energy and irradiation geometry for this particular tumour treatment. Several challenges, starting from laser-target interaction and beam transport development up to dosimetry and radiobiology, need to be overcome in order to reach the ELIMED final goals. A crucial role will be played by the final design and realization of a transport beamline capable to provide ion beams with proper characteristics in terms of energy spectrum and angular distribution which will allow performing dosimetric tests and biological cell irradiation. A first prototype of the transport beamline has been already designed and other transport elements are under construction in order to perform a first experimental test with the TARANIS laser system by the end of 2013. A wide international collaboration among specialists of different disciplines like Physics, Biology, Chemistry, Medicine and medical doctors coming from Europe, Japan, and the US is growing up around the ELIMED project with the aim to work on the conceptual design, technical and experimental realization of this core beamline of the ELI Beamlines facility. © (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
- Subjects :
- Physics
Ion beams
Lasers
Melanoma
Radiation dosimetry
Medicine
Biology
Chemistry
Eye
business.industry
Context (language use)
Laser acceleration
Laser
01 natural sciences
3. Good health
010305 fluids & plasmas
law.invention
Hadron therapy
Optics
Conceptual design
Beamline
law
0103 physical sciences
Energy spectrum
Biological cell
Aerospace engineering
010306 general physics
business
Beam (structure)
Subjects
Details
- ISSN :
- 0277786X
- Database :
- OpenAIRE
- Journal :
- SPIE Proceedings
- Accession number :
- edsair.doi.dedup.....8a7404bfb4b2febd3e02792630f70716