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Response criteria for phase II studies of supratentorial malignant glioma
- Source :
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 8(7)
- Publication Year :
- 1990
-
Abstract
- We suggest "new" response criteria for phase II studies of supratentorial malignant glioma and favor rigorous criteria similar to those in medical oncology, with important modifications. Four response categories are proposed: complete response (CR), partial response (PR), stable disease (SD), and progressive disease (PD). Response in this scheme is based on major changes in tumor size on the enhanced computed tomographic (CT) or magnetic resonance imaging (MRI) scan. Scan changes are interpreted in light of steroid use and neurologic findings. We advocate careful patient selection, emphasize pitfalls in the assessment of response, and suggest guidelines to minimize misinterpretations of response.
- Subjects :
- Cancer Research
medicine.medical_specialty
Pathology
Recurrent Glioma
Medical Oncology
Stable Disease
Glioma
medicine
Humans
Diagnostic Errors
Pseudoprogression
medicine.diagnostic_test
business.industry
Supratentorial Neoplasm
Supratentorial Neoplasms
Magnetic resonance imaging
medicine.disease
Magnetic Resonance Imaging
Oncology
Drug Evaluation
Tomography
Radiology
business
Tomography, X-Ray Computed
Progressive disease
Subjects
Details
- ISSN :
- 0732183X
- Volume :
- 8
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology
- Accession number :
- edsair.doi.dedup.....8a07b0cd87b2ec21aa43e4619636ab1d