QFR Versus FFR Derived From Computed Tomography for Functional Assessment of Coronary Artery Stenosis

Objectives The aim of this study was to compare diagnostic performance between quantitative flow ratio (QFR) derived from coronary angiography and fractional flow reserve derived from computed tomography (FFRCT) using fractional flow reserve (FFR) as the reference standard. Background QFR and FFRCT are recently developed, less invasive techniques for functional assessment of coronary artery disease. Methods QFR, FFRCT, and FFR were measured in 152 patients (233 vessels) with stable coronary artery disease. Results QFR was highly correlated with FFR (r = 0.78; p Conclusions QFR and FFRCT showed significant correlation with FFR. Mismatches between QFR and FFR and between FFRCT and FFR were frequent.