Severe Intrauterine Growth Restriction, Thrombocytopenia, and Direct Hyperbilirubinemia in a 26-week Premature Infant

A 5-day-old symmetric severely growth-restricted preterm newborn with thrombocytopenia, anemia, and direct hyperbilirubinemia has abnormal cranial ultrasonography findings (Figs 1A and 1B, 2A and 2B). Figure 1. Cranial ultrasound. A, Coronal view. B, Sagittal view. Showing hyperechoic area (arrows) suggestive of cortical calcification. Figure 2. Cranial ultrasound. A, Sagittal view. B, Coronal view. Showing area of encephalomalacia (arrows) within the upper right temporal/lower parietal lobe and with effacement of the right lateral ventricle due to mass effect. ### Prenatal and Birth Histories