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A Novel Oxazolidinone, Contezolid (MRX-I), Expresses Anti-Mycobacterium abscessus Activity
- Source :
- Antimicrobial Agents and Chemotherapy
- Publication Year :
- 2021
-
Abstract
- An evaluation of the anti- Mycobacterium abscessus activity expressed by a novel oxazolidinone, contezolid (MRX-I), toward 12 reference strains and 194 clinical isolates was conducted. Contezolid was active against M. abscessus in vitro , with effects comparable to the anti- M. abscessus effects of linezolid both extracellularly and intracellularly.
- Subjects :
- Pyridones
Mycobacterium Infections, Nontuberculous
Drug resistance
Microbial Sensitivity Tests
Mycobacterium abscessus
contezolid (MRX-I)
Microbiology
chemistry.chemical_compound
Medicine
Humans
Pharmacology (medical)
Oxazolidinones
Pharmacology
biology
business.industry
in vitro
oxazolidinone
biology.organism_classification
bacterial infections and mycoses
intracellular
In vitro
Anti-Bacterial Agents
Infectious Diseases
chemistry
Susceptibility
Linezolid
bacteria
business
Subjects
Details
- ISSN :
- 10986596
- Volume :
- 65
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Antimicrobial agents and chemotherapy
- Accession number :
- edsair.doi.dedup.....898bf94ceabd657e5e1750ce7d017d06