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The keys to control a COVID-19 outbreak in a haemodialysis unit
- Source :
- Clinical Kidney Journal
- Publication Year :
- 2020
- Publisher :
- Oxford University Press (OUP), 2020.
-
Abstract
- Background The high rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreading represents a challenge to haemodialysis (HD) units. While fast isolation of suspected cases plays an essential role to avoid disease outbreaks, significant rates of asymptomatic cases have recently been described. After detecting an outbreak in one of our HD clinics, wide SARS-CoV-2 screening and segregation of confirmed cases were performed. Methods The entire clinic population, 192 patients, underwent testing for SARS-CoV-2 detection by real-time reverse-transcriptase polymerase chain reaction . We used univariate and multivariate logistic regression to define variables involved in SARS-CoV-2 infection in our dialysis unit. Later, we analysed differences between symptomatic and asymptomatic SARS-CoV-2-positive patients. Results In total, 22 symptomatic and 14 of the 170 asymptomatic patients had a SARS-CoV-2-positive result. Living in a nursing home/homeless [odds ratio (OR) 3.54; P = 0.026], having been admitted to the reference hospital within the previous 2 weeks (OR 5.19; P = 0.002) and sharing health-care transportation with future symptomatic (OR 3.33; P = 0.013) and asymptomatic (OR 4.73; P = 0.002) positive patients were independent risk factors for a positive test. Nine positive patients (25.7%) remained asymptomatic after a 3-week follow-up. We found no significant differences between symptomatic and asymptomatic SARS-CoV-2-positive patients. Conclusions Detection of asymptomatic SARS-CoV-2-positive patients is probably one of the key points to controlling an outbreak in an HD unit. Sharing health-care transportation to the dialysis unit, living in a nursing home and having been admitted to the reference hospital within the previous 2 weeks, are major risk factors for SARS-CoV-2 infection.
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Population
030232 urology & nephrology
outcomes
Logistic regression
Asymptomatic
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
risk factors
030212 general & internal medicine
AcademicSubjects/MED00340
education
Dialysis
education.field_of_study
Transplantation
outbreak
business.industry
COVID-19
Outbreak
Original Articles
Odds ratio
haemodialysis
Nephrology
dialysis
Hemodialysis
asymptomatic carriers
medicine.symptom
business
Asymptomatic carrier
Subjects
Details
- Language :
- English
- ISSN :
- 20488513
- Database :
- OpenAIRE
- Journal :
- Clinical Kidney Journal
- Accession number :
- edsair.doi.dedup.....8972c61503be33bf5d1032252a70086b
- Full Text :
- https://doi.org/10.1093/ckj/sfaa119