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Evaluation of Cytotoxic and Genotoxic Effects in Human Peripheral Blood Leukocytes Following Exposure to 1950-MHz Modulated Signal
Evaluation of Cytotoxic and Genotoxic Effects in Human Peripheral Blood Leukocytes Following Exposure to 1950-MHz Modulated Signal
- Source :
- IEEE transactions on plasma science 34 (2006): 1441–1448. doi:10.1109/TPS.2006.878379, info:cnr-pdr/source/autori:Sannino A; Calabrese ML; D'Ambrosio G; Massa R; Petraglia G; Mita P; Sarti M; Scarfì MR;/titolo:Evaluation of cytotoxic and genotoxic effects in human peripheral blood leukocytes following exposure to 1950-MHz modulated signal/doi:10.1109%2FTPS.2006.878379/rivista:IEEE transactions on plasma science/anno:2006/pagina_da:1441/pagina_a:1448/intervallo_pagine:1441–1448/volume:34
- Publication Year :
- 2006
- Publisher :
- Institute of Electrical and Electronics Engineers (IEEE), 2006.
-
Abstract
- Human peripheral blood leukocytes from six volunteers were exposed to a Universal Mobile Telecommunication System (UMTS) signal (frequency carrier of 1950 MHz) for 24 h. The exposures were carried out in a waveguide system at specific absorption rates (SAR) of 0.5 and 2.0 W/kg, and for each blood donor, sham-exposed samples were also set up. The alkaline comet assay was used to quantify DNA damage, while cytotoxicity was determined by the Trypan blue exclusion method. The results obtained indicate the absence of genotoxic and cytotoxic effects at both SAR levels investigated, as assessed by comparing sham-exposed and exposed samples. Therefore, the findings indicate that, in the experimental conditions adopted, 24-h in vitro exposure to 1950-MHz radio-frequency radiation (UMTS signal) does not induce DNA damage in human leukocytes.
- Subjects :
- Cell viability
Nuclear and High Energy Physics
Chemistry
DNA damage
Absorption (skin)
Condensed Matter Physics
Radiation effect
Molecular biology
Comet assay
chemistry.chemical_compound
comet assay
Universal Mobile Telecommunication System (UMTS) signal
Cytotoxic T cell
Trypan blue
Viability assay
radio-frequency radiation
Cytotoxicity
human leukocytes
Cell viability, comet assay, human leukocytes, radiofrequency radiation, Universal Mobile Telecommunication System (UMTS) signal
Subjects
Details
- ISSN :
- 19399375 and 00933813
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- IEEE Transactions on Plasma Science
- Accession number :
- edsair.doi.dedup.....894cfd5749bdd7b6dc16502d55db80f0
- Full Text :
- https://doi.org/10.1109/tps.2006.878379