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Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit

Authors :
K. Murakami
Susanna Guatelli
Vladimir Ivanchenko
Takashi Sasaki
Jeremy M. C. Brown
Ioanna Kyriakou
E. Delage
Mario A. Bernal
H. Payno
Marie-Claude Bordage
Ivan Petrović
Sylvain Meylan
Q.T. Pham
Aleksandra Ristić-Fira
Shirin A. Enger
Yann Perrot
Ziad Francis
Václav Štěpán
Shogo Okada
Z. El Bitar
M. Karamitros
Carmen Villagrasa
Lydia Maigne
Sebastien Incerti
Marie Davídková
H.N. Tran
Instituto de Fisica 'Gleb Wataghin'
Universidade Estadual de Campinas (UNICAMP)
Centre de Recherches en Cancérologie de Toulouse (CRCT)
Université Toulouse III - Paul Sabatier (UT3)
Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
School of Mathematics and Physics [Belfast]
Queen's University [Belfast] (QUB)
School of Physics and Astronomy [Clayton]
Monash University [Clayton]
Department of Radiation Dosimetry
Nuclear Physics Institute of the AS CR
Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC)
Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
Institut Pluridisciplinaire Hubert Curien (IPHC)
Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)
Medical Physics Unit, Department of Oncology
McGill University = Université McGill [Montréal, Canada]
Department of Physics, Faculty of Sciences
Université Saint-Joseph de Beyrouth (USJ)
Centre for Medical Radiation Physics
University of Wollongong [Australia]
Geant4 Associates International Ltd
Ecoanalytica
Notre Dame Radiation Laboratory
University of Notre Dame [Indiana] (UND)
Medical Physics Laboratory
Medical School University of Ioannina
Institut de Radioprotection et de Sûreté Nucléaire (IRSN)
KEK (High energy accelerator research organization)
Vinča Institute of Nuclear Sciences
University of Belgrade [Belgrade]
Division of Nuclear Physics
Tong Duc Thang University
Faculty of Applied Sciences
Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG)
Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
Nuclear Physics Institute of the ASCR
Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)
McGill University
University of Wollongong
High Energy Accelerator Research Organization (KEK)
University of Tsukuba
Universidade Estadual de Campinas = University of Campinas (UNICAMP)
Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
University of Ioannina
Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
Source :
Physica Medica, Physica Medica, Elsevier, 2015, 31 (8), pp.861-874. ⟨10.1016/j.ejmp.2015.10.087⟩, Physica Medica, 2015, 31 (8), pp.861-874. ⟨10.1016/j.ejmp.2015.10.087⟩
Publication Year :
2015
Publisher :
HAL CCSD, 2015.

Abstract

International audience; Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of today's radiobiology research. The Monte Carlo simulation of physical, physicochemical and chemical processes involved may provide a powerful tool for the simulation of early damage induction. The Geant4-DNA extension of the general purpose Monte Carlo Geant4 simulation toolkit aims to provide the scientific community with an open source access platform for the mechanistic simulation of such early damage. This paper presents the most recent review of the Geant4-DNA extension, as available to Geant4 users since June 2015 (release 10.2 Beta). In particular, the review includes the description of new physical models for the description of electron elastic and inelastic interactions in liquid water, as well as new examples dedicated to the simulation of physicochemical and chemical stages of water radiolysis. Several implementations of geometrical models of biological targets are presented as well, and the list of Geant4-DNA examples is described.

Details

Language :
English
ISSN :
11201797
Database :
OpenAIRE
Journal :
Physica Medica, Physica Medica, Elsevier, 2015, 31 (8), pp.861-874. ⟨10.1016/j.ejmp.2015.10.087⟩, Physica Medica, 2015, 31 (8), pp.861-874. ⟨10.1016/j.ejmp.2015.10.087⟩
Accession number :
edsair.doi.dedup.....894b005666d291d2b7118dff73088cfb
Full Text :
https://doi.org/10.1016/j.ejmp.2015.10.087⟩