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Ion concentration measurement using synthetic microfluidic papers
- Source :
- PLoS ONE, Vol 15, Iss 11, p e0242188 (2020), PLoS ONE
- Publication Year :
- 2020
- Publisher :
- Public Library of Science (PLoS), 2020.
-
Abstract
- Non-invasive diagnosis on biological liquid samples, such as urine, sweat, saliva, and tears, may allow patients to evaluate their health by themselves. To obtain accurate diagnostic results, target liquid must be precisely sampled. Conventionally, urine sampling using filter paper can be given as an example sampling, but differences in the paper structure can cause variations in sampling volume. This paper describes precise liquid sampling using synthetic microfluidic papers, which are composed of obliquely combined micropillars. Sampling volume accuracy was investigated using different designs and collection methods to determine the optimal design and sample collecting method. The optimized protocol was followed to accurately measure potassium concentration using synthetic microfluidic paper and a commercially available densitometer, which verified the usefulness of the synthetic microfluidic papers for precision sampling.
- Subjects :
- Physiology
Computer science
Potassium
Microfluidics
02 engineering and technology
Urine
01 natural sciences
Filter Paper
Medicine and Health Sciences
Densitometer
Measurement
Multidisciplinary
Sampling (statistics)
021001 nanoscience & nanotechnology
Body Fluids
Laboratory Equipment
Chemistry
Blood
Point-of-Care Testing
Physical Sciences
Engineering and Technology
Medicine
Fluidics
Anatomy
0210 nano-technology
Biological system
Research Article
Chemical Elements
Paper
Sample (material)
Science
Densitometers
Equipment
chemistry.chemical_element
Urinalysis
Humans
Saliva
Measurement Equipment
Filter paper
010401 analytical chemistry
Biology and Life Sciences
Membranes, Artificial
0104 chemical sciences
chemistry
Urine sample
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 15
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....8943cf59591327a9dedbb96657195daa