Circulating interferon‐α measured with a highly sensitive assay as a biomarker for juvenile inflammatory myositis activity: Comment on the Article by Mathian et al

Comment on: Monitoring Disease Activity in Systemic Lupus Erythematosus With Single-Molecule Array Digital Enzyme-Linked Immunosorbent Assay Quantification of Serum Interferon-α’ by Mathian et al; International audience; Letter to the editorWe read with interest the study of Mathian et al (1), suggesting that direct serum IFNα determination with a highly sensitive assay might be useful for disease activity monitoring in systemic lupus erythematosus (SLE). More generally, the identification of reactive biomarkers is highly desirable in many disease states, including idiopathic inflammatory myositis (IIM).