Back to Search
Start Over
Efficacy and safety of Shenfu injection for patients with return of spontaneous circulation after sudden cardiac arrest
- Source :
- Medicine
- Publication Year :
- 2018
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2018.
-
Abstract
- Background: Sudden cardiac arrest (SCA) is one of the most common critical illnesses encountered in clinical practice. Shenfu injection (SFI) has received extensive attention as an alternative therapy that can effectively maintain the autonomic circulation function after cardiopulmonary resuscitation. However, the mechanism of SFI is not yet fully understood. In addition, there has been no systematic review or meta-analysis of SFI in the treatment of patients with return of spontaneous circulation after SCA. Herein, we describe the protocol of a proposed study based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines that aims to systematically evaluate the efficacy and safety of SFI in patients with return of spontaneous circulation after SCA. Methods: Two researchers will search 9 electronic databases (PubMed, Medline, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and Chinese Biomedical Database) to identify all studies that meet the inclusion criteria and were published before July 2018. After information extraction and methodological quality evaluation, we will use Stata 13.0 software (STATA Corporation, College Station, TX, USA) to synthesize the data. The primary outcomes will be the survival rate and Glasgow Coma Scale. Results: The data synthesis results will objectively illustrate the efficacy and safety of SFI in patients with return of spontaneous circulation after SCA. Conclusion: The findings will provide a reference for the use of SFI in the treatment of patients with return of spontaneous circulation after SCA. Registration: PROSPERO (registration number: CRD42018104230).
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
MEDLINE
030204 cardiovascular system & hematology
Return of spontaneous circulation
Cochrane Library
Injections
03 medical and health sciences
0302 clinical medicine
Clinical Protocols
systematic review
sudden cardiac arrest
Study Protocol Systematic Review
Humans
return of spontaneous circulation
Medicine
protocol
Shenfu injection
Cardiopulmonary resuscitation
Intensive care medicine
business.industry
Glasgow Coma Scale
Sudden cardiac arrest
General Medicine
Cardiopulmonary Resuscitation
Heart Arrest
Death, Sudden, Cardiac
Treatment Outcome
Systematic review
Meta-analysis
medicine.symptom
business
030217 neurology & neurosurgery
Drugs, Chinese Herbal
Systematic Reviews as Topic
Research Article
Subjects
Details
- ISSN :
- 00257974
- Volume :
- 97
- Database :
- OpenAIRE
- Journal :
- Medicine
- Accession number :
- edsair.doi.dedup.....887230274574e1408c9bc7eac6f03782