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Illness insight and neurophysiological error-processing deficits in schizophrenia
- Source :
- Schizophrenia research. 156(1)
- Publication Year :
- 2014
-
Abstract
- Impaired illness insight in schizophrenia is associated with non-adherence and worse outcomes. Schizophrenia patients also exhibit error-monitoring deficits, which have been proposed to cause poor insight. To test this hypothesis, we examined whether schizophrenia patients' deficits in neurophysiological error-monitoring indices, the error-related negativity (ERN) and error positivity (Pe) event-related potential (ERP) amplitudes, are associated with impaired insight. ERPs were recorded in 18 schizophrenia patients and 18 normal comparison participants during a Stroop task. Patients' subnormal ERN and Pe amplitudes did not correlate with insight, suggesting that impaired insight in schizophrenia stems from neurocognitive mechanisms other than deficient error monitoring. Canadian Institutes of Health Research (INO-112359)
- Subjects :
- Adult
Male
medicine.medical_specialty
Statistics as Topic
Neurophysiology
Audiology
Neuropsychological Tests
behavioral disciplines and activities
Error-related negativity
Cognition
Event-related potential
mental disorders
medicine
Reaction Time
Error processing
Humans
Illness insight
Psychiatry
Evoked Potentials
Biological Psychiatry
Problem Solving
Analysis of Variance
Electroencephalography
Middle Aged
medicine.disease
Electrophysiology
Psychiatry and Mental health
Schizophrenia
Error positivity
Female
Schizophrenic Psychology
Psychology
Cognition Disorders
Neurocognitive
Event-related potentials
Stroop effect
Subjects
Details
- ISSN :
- 15732509
- Volume :
- 156
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Schizophrenia research
- Accession number :
- edsair.doi.dedup.....886b303a96e55094253e6b5ec5eff0f5