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Utility of point-of-care urine trypsinogen dipstick test for diagnosing acute pancreatitis in an emergency unit

Authors :
Harjeet Singh
Deba Prasad Dhibar
Ashok Kumar Pannu
Vishal Sharma
Navneet Sharma
Atul Saroch
Amar Simha
Source :
Biomarkers in Medicine. 15:1271-1276
Publication Year :
2021
Publisher :
Future Medicine Ltd, 2021.

Abstract

Background: A point-of-care diagnostic test for acute pancreatitis could help in early triage and management of this condition. Materials & methods: Urine trypsinogen dipstick test (UTDT) was performed in consecutive cases suspected to have acute pancreatitis and diagnostic accuracy calculated. Results: Of 187 patients, 90 were have acute pancreatitis and UTDT was positive in 61 (67.7%). In the 97 non pancreatitis cases, UTDT was positive in nine (9.3%). The sensitivity and specificity of UTDT for acute pancreatitis was 67.8% and 90.7%, respectively. In patients presenting within 3 days of abdominal pain, sensitivity and specificity were 72.7% and 91.8%, respectively. Discussion: While offering the possibility of a point of care diagnosis, the low sensitivity of UTDT could be a concern with its routine use.

Details

ISSN :
17520371 and 17520363
Volume :
15
Database :
OpenAIRE
Journal :
Biomarkers in Medicine
Accession number :
edsair.doi.dedup.....87eb017ef5904dc718cb1e0ae6515ac8