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Maternal Intake of Flaxseed During Lactation and Exercise Training Protect Against Salt Overload-Induced Aortic Remodeling in Adult Offspring
- Source :
- International Journal of Cardiovascular Sciences, Issue: ahead, Published: 06 NOV 2020, International Journal of Cardiovascular Sciences v.34 n.2 2021, International Journal of Cardiovascular Sciences, Sociedade Brasileira de Cardiologia (SBC), instacron:SBC, International Journal of Cardiovascular Sciences, Volume: 34, Issue: 2, Pages: 124-133, Published: 06 NOV 2020
- Publication Year :
- 2020
- Publisher :
- Sociedade Brasileira de Cardiologia, 2020.
-
Abstract
- Background High dietary sodium intake can induce endothelial stiffness even without changes in blood pressure. Objectives To evaluate the effects of exercise training and chronic intake of sodium chloride solution on aortic morphology of male offspring of rat dams who consumed flaxseed during lactation. Methods Female rats were fed with a control diet or a flaxseed diet during lactation. At weaning, two male offspring of each rat dam were allocated into eight groups for 180 days: four groups received a control diet e four received a flaxseed diet, with /without exercise and with/without NaCl solution supply. Aorta was collected for histomorphometric analysis. The one-way analysis of variance was used and P value < 0.05 was considered statistically significant. Results The chronic use of 1% NaCl solution led to changes in aortic histoarchitecture in the control group: increase in aortic intima-media thickness (10,4%, p
- Subjects :
- Offspring
Sodium
Metabolism/physiology
Physiology
chemistry.chemical_element
Fatty Acids,Omega-3
02 engineering and technology
Fatty acids.omega 3
Adult offspring
Lactation
0202 electrical engineering, electronic engineering, information engineering
Medicine
Weaning
Exercise
business.industry
Dietary sodium intake
020206 networking & telecommunications
Rats
Blood pressure
medicine.anatomical_structure
chemistry
cardiovascular system
Flaxseed Diet
020201 artificial intelligence & image processing
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- International Journal of Cardiovascular Sciences, Issue: ahead, Published: 06 NOV 2020, International Journal of Cardiovascular Sciences v.34 n.2 2021, International Journal of Cardiovascular Sciences, Sociedade Brasileira de Cardiologia (SBC), instacron:SBC, International Journal of Cardiovascular Sciences, Volume: 34, Issue: 2, Pages: 124-133, Published: 06 NOV 2020
- Accession number :
- edsair.doi.dedup.....879ee959135defe8d638d49ab7850dbd