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Screening of Various Hormone-Sensitive Lipase Inhibitors as Endocannabinoid-Hydrolyzing Enzyme Inhibitors
- Source :
- ChemMedChem. 4:1253-1259
- Publication Year :
- 2009
- Publisher :
- Wiley, 2009.
- Subjects :
- Cannabinoid receptor
Adipose tissue
Hormone-sensitive lipase
Pharmacology
Crystallography, X-Ray
01 natural sciences
Biochemistry
Amidohydrolases
Mice
Structure-Activity Relationship
03 medical and health sciences
In vivo
Drug Discovery
Animals
Computer Simulation
Enzyme Inhibitors
General Pharmacology, Toxicology and Pharmaceutics
030304 developmental biology
chemistry.chemical_classification
Oxadiazoles
0303 health sciences
Binding Sites
010405 organic chemistry
Chemistry
Drug discovery
Hydrolysis
Organic Chemistry
Sterol Esterase
Endocannabinoid system
Monoacylglycerol Lipases
0104 chemical sciences
Monoacylglycerol lipase
Enzyme
Drug Design
Benzamides
Molecular Medicine
Carbamates
Subjects
Details
- ISSN :
- 18607179
- Volume :
- 4
- Database :
- OpenAIRE
- Journal :
- ChemMedChem
- Accession number :
- edsair.doi.dedup.....87692ed8ece370f2ff7b58090ca51cf0
- Full Text :
- https://doi.org/10.1002/cmdc.200900137