Enhancing the Anti-Erosive Properties of Fluoride and Stannous with the Polymer Carbopol

Made available in DSpace on 2021-06-25T11:04:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-10-01 This in vitro study investigated whether Carbopol 980 polymer could potentiate the anti-erosive effect of solutions containing sodium fluoride (F) and sodium fluoride associated with stannous chloride (FS). The dissolution of hydroxyapatite treated with the experimental solutions (F [500 ppm F-], F + Carbopol [0.1%], FS [500 ppm F- + 800 ppm Sn2+], FS + Carbopol) was evaluated. Deionized water was the negative control, and a commercial mouth rinse (AmF/NaF/SnCl2; 500 ppm F + 800 ppm Sn2+; Elmex® Erosion Protection) was the positive control. The solutions were also evaluated in an erosion-rehardening protocol, with two treatments per day, using bovine enamel specimens (n = 15) and human saliva. The acid challenge was performed using 0.3% citric acid (pH 2.6) for 2 min. Microhardness was measured at different times: baseline, after the first erosive challenge, after treatment, and after the second erosive challenge. Based on microhardness values, the demineralization, rehardening, and protective potentials were calculated. The alkali-soluble fluoride on enamel surfaces was also measured. Data were analyzed using ANOVA and Tukey tests (α = 0.05). Groups treated with FS + Carbopol showed the lowest hydroxyapatite dissolution and the highest rehardening and protective potentials. The measurement of alkali-soluble fluoride on enamel surfaces was also higher in the FS + Carbopol group. Carbopol was able to significantly increase the protective effect of the fluoridated solutions in addition to optimizing the adsorption of fluoride on the enamel surface. Department of Restorative Dentistry Institute of Science and Technology São Paulo State University - UNESP Avenida Engenheiro Francisco José Longo, 777, Jardim São Dimas Department of Restorative Dentistry Dental School University of Taubaté Department of Restorative Dentistry São Paulo University - USP Department of Chemical Engineering Polytechnic School São Paulo University - USP Department of Restorative Dentistry Institute of Science and Technology São Paulo State University - UNESP Avenida Engenheiro Francisco José Longo, 777, Jardim São Dimas