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Development and Validation of a LC-MS/MS Method for Determination of Multi-Class Antibiotic Residues in Aquaculture and River Waters, and Photocatalytic Degradation of Antibiotics by TiO2 Nanomaterials

Development and Validation of a LC-MS/MS Method for Determination of Multi-Class Antibiotic Residues in Aquaculture and River Waters, and Photocatalytic Degradation of Antibiotics by TiO2 Nanomaterials

Authors :
Tuan Duc Nguyen
Duy Quoc Nguyen
Tho Chau Minh Vinh Do
Phuoc Huu Le
Source :
Catalysts, Vol 10, Iss 3, p 356 (2020), Catalysts, Volume 10, Issue 3
Publication Year :
2020
Publisher :
MDPI AG, 2020.

Abstract

This study presents a multi-residue method for simultaneous qualitative and quantitative analysis of eight antibiotics from some common classes, including beta-lactam, tetracyclines, lincosamides, glycopeptides, and sulfonamides in 39 aquaculture and river water samples from the Mekong Delta (Vietnam) using liquid chromatography-tandem mass spectrometry (LC-MS/MS). As a result, doxycycline (DXC), oxytetracycline (OTC), lincomycin (LCM), sulfamethoxazole (SMX), and sulfamethazine (SMZ) were detected with high frequency over 65% and an average concentration of 22.6&ndash<br />76.8 ng&middot<br />mL&minus<br />1. The result suggests that antibiotic residues in the aquaculture and river waters are considered as an emerging environmental problem of the region. To address this issue, we fabricated the well-defined TiO2 nanotube arrays (TNAs) and nanowires on nanotube arrays (TNWs/TNAs) using the anodization method. The TNAs had an inner tube diameter of ~95 nm and a wall thickness of ~25 nm. Meanwhile, the TNWs/TNAs had a layer of TiO2 nanowires with a length of ~6 &micro<br />m partially covering the TNAs. In addition, both TNAs and TNWs/TNAs had pure anatase phase TiO2 with (101) and (112) dominant preferred orientations. Moreover, the TNAs and TNWs/TNAs effectively and rapidly degraded the antibiotic residues under UV-VIS irradiation at 120 mW/cm2 and obtained over 95% removal at 20 min. Indeed, the photocatalytic reaction rate constants (k) were in the range of 0.14&ndash<br />0.36 min&minus<br />1 for TNAs, and 0.15&ndash<br />0.38 min&minus<br />1 for TNWs/TNAs. Noticeably, the k values of TNWs/TNAs were slightly higher than those of TNAs for LCM, DXC, OTC, SMZ, and SMX that could be attributed to the larger surface area of TNWs/TNAs than TNAs when TNWs/TNAs had an additional ~6&mu<br />m TNWs top layer.

Details

ISSN :
20734344
Volume :
10
Database :
OpenAIRE
Journal :
Catalysts
Accession number :
edsair.doi.dedup.....870d108e3cbd63a291649d00ae6578c5
Full Text :
https://doi.org/10.3390/catal10030356