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Rising Incidence of Acute Hospital Admissions due to Gout
- Source :
- The Journal of rheumatology. 47(4)
- Publication Year :
- 2019
-
Abstract
- Objective.To describe trends in acute hospital admissions due to gout in England, with rheumatoid arthritis (RA) as a comparator, alongside prescribing trends for common gout medications.Methods.An ecological study was performed using UK National Health Service (NHS) Digital Hospital Episode Statistics data to calculate the incidence of unplanned admissions with primary diagnoses of gout or RA in adults in England between April 2006 and March 2017. NHS Digital Community Prescription data for allopurinol, febuxostat, and colchicine were considered over a similar period.Results.The incidence of unplanned gout admissions increased by 58.4% over the study period, from 7.9 admissions per 100,000 population in 2006/07 to 12.5 admissions per 100,000 population in 2016/17 (p < 0.0001). Gout admissions increased as a proportion of all hospital admissions, and accounted for 349,768 bed-days cumulatively. Unplanned RA admissions halved over the study period, from 8.6 admissions per 100,000 population in 2006/07 to 4.3 admissions per 100,000 population in 2016/17 (p < 0.0001). Community prescriptions dispensed for allopurinol and colchicine have increased by 71.4% and 165.6%, respectively, since 2006 (p < 0.0001). Febuxostat prescriptions have increased 20-fold since 2010 (p < 0.0001), when prescription data became available.Conclusion.Acute gout admissions in England increased between 2006 and 2017, accompanied by increasing prescription of gout therapies. Acute admissions due to RA halved over the same time period. These data call for aggressive target-driven therapy for this highly treatable disease.
- Subjects :
- Adult
medicine.medical_specialty
Gout
Allopurinol
Immunology
Population
State Medicine
Gout Suppressants
Febuxostat
Rheumatology
Epidemiology
medicine
Immunology and Allergy
Humans
Medical prescription
education
education.field_of_study
business.industry
Incidence (epidemiology)
Incidence
Ecological study
medicine.disease
Hospitals
Emergency medicine
business
medicine.drug
Subjects
Details
- ISSN :
- 0315162X
- Volume :
- 47
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- The Journal of rheumatology
- Accession number :
- edsair.doi.dedup.....86f6992ee97addd49f54e81f468508f0