Time-related changes of metabolic and physicochemical profiles in patients with mechanical ileal neobladders

OBJECTIVE To investigate metabolic disturbances, possibly leading to stone disease, in the Camey II technique for creating a urinary reservoir from an intestinal segment. PATIENTS, SUBJECTS AND METHODS Thirty patients with a Camey II ileal neobladder and 26 controls had metabolic investigations of blood samples, and 24-h and fasting urine samples, to assess renal function, the risk of stone formation, and bone turnover. The state of saturation with calcium oxalate, uric acid and brushite were calculated using a computer program. RESULTS The patients had lower renal clearances than the controls (P