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Alterations in Human Dermal Connective Tissue with Age and Chronic Sun Damage
- Source :
- Journal of Investigative Dermatology. 39(4):347-350
- Publication Year :
- 1962
- Publisher :
- Elsevier BV, 1962.
-
Abstract
- Aged unexposed human skin has decreased hexosamine (22), decreased solubility of dermal collagen (1), and increased hydroxyproline (22), with few dramatic histological alterations (8) as compared with young skin. In contrast, the identity of the histopathologic changes in chronically sun-damaged skin (actinic elastosis) has been debated for many years (5, 6, 9, 10, 23). These changes in exposed skin are caused primarily by prolonged and repeated actinic damage (7,8,11,21,23).
- Subjects :
- Pathology
medicine.medical_specialty
Aging
Actinic Damage
Connective tissue
Human skin
Dermatology
Biochemistry
Hydroxyproline
chemistry.chemical_compound
medicine
Humans
Molecular Biology
Skin
Dermal collagen
integumentary system
business.industry
Sun damage
Cell Biology
Actinic elastosis
medicine.disease
Radiation Effects
medicine.anatomical_structure
chemistry
Connective Tissue
Sunlight
business
Subjects
Details
- ISSN :
- 0022202X
- Volume :
- 39
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of Investigative Dermatology
- Accession number :
- edsair.doi.dedup.....86d921fe5b1685e9e37cc9d75757d71c
- Full Text :
- https://doi.org/10.1038/jid.1962.122