Back to Search
Start Over
Performance of TEM-PCR vs Culture for Bacterial Identification in Pediatric Musculoskeletal Infections
- Source :
- Open Forum Infectious Diseases
- Publication Year :
- 2018
- Publisher :
- Oxford University Press (OUP), 2018.
-
Abstract
- Improved diagnostics are needed for children with musculoskeletal infections (MSKIs). We assessed the performance of target-enriched multiplex polymerase chain reaction (TEM-PCR) in children with MSKI. TEM-PCR was concordant with culture in pathogen identification and antibiotic susceptibility testing, while increasing the overall yield of pathogen detection. This technology has the potential to inform judicious antimicrobial use early in the disease course.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Pathology
Pathogen detection
pediatrics
medicine.drug_class
030106 microbiology
Antibiotics
Clinical Neurology
musculoskeletal infections
law.invention
03 medical and health sciences
0302 clinical medicine
law
030225 pediatrics
Internal medicine
Multiplex polymerase chain reaction
diagnostics
medicine
septic arthritis
Pathogen
Polymerase chain reaction
business.industry
Brief Report
Osteomyelitis
osteomyelitis
medicine.disease
3. Good health
Infectious Diseases
Oncology
Identification (biology)
Septic arthritis
business
Subjects
Details
- ISSN :
- 23288957
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Open Forum Infectious Diseases
- Accession number :
- edsair.doi.dedup.....86d6b738c765697b3edbc8a902495367