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Supplementary Data from The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer

Authors :
Gustavo A. Miranda-Carboni
Susan A. Krum
Victoria Seewaldt
Tiffany N. Seagroves
William E. Lowry
Ruth M. O'Regan
Lily Yang
Lisa D. Yee
Robert Cardiff
Andrew C. White
Raisa I. Krutilina
Hilaire C. Barch
Stephan Lehr
Joseph K. Gray
Wendy Silva
Julio Silva
William L. Kuenzinger
Stephanie Runke
Jackelyn A. Alva-Ornelas
Peter Wend
Iram Fatima
Ikbale El Ayachi
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Section: 1) Seven supplementary figures and legends: A. Supplementary figure S1: TCGA analysis of WNT10B network. B. Supplementary figure S2: Human IHC analysis of WNT10B, HMGA2 and EZH2. C. Supplementary figure S3: Mouse IHC analysis of HMGA2 and EZH2. D. Supplementary figure S4: ChIP, qPCR and IB analysis on WNT10B/�CATENIN direct target genes. E. Supplementary figure S5: Characterization of CRISPR HMGA2KO and EZH2KO cells both in vitro and in vivo. F. Supplementary figure S6: Validation of WNT10B network on TNBC PDX tumors. G. Supplementary figure S7: Isobologram curves of ICG-001 and Doxorubicin activity. 2) Supplementary Material & Methods 3) Supplementary Table 1 (ST1) qPCR primers 4) Supplementary Table 2 (ST2) ChIP primers 5) 6) Supplementary Table 3 (ST3) drug combinatorial index

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....86d588ad2842fb0c7dd56c5ab217cf0a
Full Text :
https://doi.org/10.1158/0008-5472.22422239.v1