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Supplemental Table S6 from High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma

Authors :
Brian D. Crompton
Kimberly Stegmaier
Mindy I. Davis
Jason N. Berman
Andrew Kung
Matthew D. Hall
Matthew B. Boxer
Xin Xu
Emma Hughes
Amy Wang
Madeleine E. Lemieux
Gabriela Alexe
Crystal McKnight
Min Shen
Kellsey Wuerthele
Amy Conway Saur
Chansey J. Veinotte
Nicole Melong
Allison F. O'Neill
Rajarshi Guha
Elizabeth E. Hwang
Sarah Wang
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplemental Table S6. Muliple metrics were used to calculate synergy of all compounds tested from MIPE 4.0 library in combination with PF-562271. Highlighted in green are Pan-Aurora Inhibitors, red are Aurora B inhibitors, and blue are Aurora A inhibitors.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....86c3579846edb03610ded5352a8f96e6
Full Text :
https://doi.org/10.1158/1078-0432.22464630