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Frontoparietal and Default Mode Network Contributions to Self-Referential Processing in Social Anxiety Disorder
- Source :
- Cognitive, Affective, & Behavioral Neuroscience. 22:187-198
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Social anxiety disorder (SAD) is characterized by negative self-referential processing, which triggers excessive emotional reactivity. In healthy individuals, positive self-views typically predominate and are supported by regions of the default mode network (DMN) that represent self-related information and regions of the frontoparietal control network (FPCN) that contribute to metacognitive awareness and emotion regulation. The current study used functional magnetic resonance imaging (fMRI) to examine patterns of DMN and FPCN activation during positive and negative self-referential judgments in SAD patients (N = 97) and controls (N = 34). As expected, SAD patients demonstrated a striking difference in self-beliefs compared with non-anxious healthy controls, endorsing fewer positive traits and more negative traits. However, SAD patients and controls demonstrated largely similar patterns of DMN and FPCN recruitment during self-referential judgements. No significant group differences were observed. However, equivalence testing identified numerous regions demonstrating effect sizes that were not small enough to conclude that they were practically equivalent to zero, despite the nonsignificant null hypothesis test. These regions may be key targets to investigate in future studies using larger samples.
- Subjects :
- Brain Mapping
medicine.medical_specialty
Future studies
medicine.diagnostic_test
Cognitive Neuroscience
Significant group
Social anxiety
Brain
Default Mode Network
Phobia, Social
Audiology
Magnetic Resonance Imaging
behavioral disciplines and activities
Self Concept
Emotional Regulation
Behavioral Neuroscience
mental disorders
medicine
Control network
Humans
Functional magnetic resonance imaging
Reactivity (psychology)
Psychology
Null hypothesis
Default mode network
Subjects
Details
- ISSN :
- 1531135X and 15307026
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Cognitive, Affective, & Behavioral Neuroscience
- Accession number :
- edsair.doi.dedup.....86b2a6a7e87cb0d18894919f73bf890b