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Acousto-Pi: An Opto-Acoustofluidic System Using Surface Acoustic Waves Controlled with Open-Source Electronics for Integrated In-Field Diagnostics
- Source :
- IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69(1), 411-422. IEEE
- Publication Year :
- 2022
-
Abstract
- Surface acoustic wave (SAW) devices are increasingly applied in life sciences, biology, and point-of-care applications due to their combined acoustofluidic sensing and actuating properties. Despite the advances in this field, there remain significant gaps in interfacing hardware and control strategies to facilitate system integration with high performance and low cost. In this work, we present a versatile and digitally controlled acoustofluidic platform by demonstrating key functions for biological assays such as droplet transportation and mixing using a closed-loop feedback control with image recognition. Moreover, we integrate optical detection by demonstrating in situ fluorescence sensing capabilities with a standard camera and digital filters, bypassing the need for expensive and complex optical setups. The Acousto-Pi setup is based on open-source Raspberry Pi hardware and 3-D printed housing, and the SAW devices are fabricated with piezoelectric thin films on a metallic substrate. The platform enables the control of droplet position and speed for sample processing (mixing and dilution of samples), as well as the control of temperature based on acousto-heating, offering embedded processing capability. It can be operated remotely while recording the measurements in cloud databases toward integrated in-field diagnostic applications such as disease outbreak control, mass healthcare screening, and food safety.
- Subjects :
- Acoustics and Ultrasonics
F300
H600
Computer science
Surface Acoustic Waves (SAWs)
Point-of-Care Systems
Cloud computing
Field (computer science)
Feedback
Electronic engineering
Electronics
Electrical and Electronic Engineering
Optical filter
Instrumentation
business.industry
Point-Of-Care (POC) diagnostics
Surface acoustic wave
Acoustic wave
Feedback control
Sound
Interfacing
Open-source electronics
System integration
Integrated acoustofluidics
business
Fluorescence imagining
Piezoelectric thin film
Subjects
Details
- Language :
- English
- ISSN :
- 08853010
- Database :
- OpenAIRE
- Journal :
- IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69(1), 411-422. IEEE
- Accession number :
- edsair.doi.dedup.....867631df7227ae02191e592c511b8b7b