Polarity development and synaptogenesis in low density primary cultures of neocortex. Use of herpes simplex virus-1 vectors to transfer genes into postmitotic neurons

'Dept of Anatomy & Physiology, University of Dundee. Dundee, DDl 4HN, UK. @Dept. of Molecular & Life Science, Dundee Institute of Technology, Dundee DDl lHG, UK. 'Institute of Virology. MRC Virology Unit, Univesity of Glasgow, Glasgow G11 SJR, UK. Fig. 1. The distribution of MAP-2 (a) and svnaptophvsin (b) in neocortical cultures after 23 da s i n vitro. In spite of their importance, little is known about how Neurons were p rocesse~ for double label l ing