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Reactive oxygen species production and antioxidant enzyme activity during epididymal sperm maturation in Corynorhinus mexicanus bats
- Source :
- Reproductive biology. 16(1)
- Publication Year :
- 2015
-
Abstract
- Prolonged sperm storage in the epididymis of Corynorhinus mexicanus bats after testicular regression has been associated with epididymal sperm maturation in the caudal region, although the precise factors linked with this phenomenon are unknown. The aim of this work is to determine the role of reactive oxygen species (ROS) and changes in antioxidant enzymatic activity occurring in the spermatozoa and epididymal fluid over time, in sperm maturation and storage in the caput, corpus and cauda of the bat epididymis. Our data showed that an increment in ROS production coincided with an increase in superoxide dismutase (SOD) activity in epididymal fluid and with a decrease in glutathione peroxidase (GPX) activity in the spermatozoa in at different time points and epididymal regions. The increase in ROS production was not associated with oxidative damage measured by lipid peroxidation. The results of the current study suggest the existence of a shift in the redox balance, which might be associated with sperm maturation and storage.
- Subjects :
- 0106 biological sciences
0301 basic medicine
Male
endocrine system
medicine.medical_specialty
Antioxidant
medicine.medical_treatment
010603 evolutionary biology
01 natural sciences
Antioxidants
Gene Expression Regulation, Enzymologic
Superoxide dismutase
Lipid peroxidation
03 medical and health sciences
chemistry.chemical_compound
Endocrinology
Internal medicine
Chiroptera
medicine
Animals
reproductive and urinary physiology
chemistry.chemical_classification
Epididymis
Reactive oxygen species
Glutathione Peroxidase
biology
urogenital system
Superoxide Dismutase
Glutathione peroxidase
Sperm
Enzyme assay
Sperm Maturation
030104 developmental biology
medicine.anatomical_structure
chemistry
biology.protein
Animal Science and Zoology
Reactive Oxygen Species
Developmental Biology
Subjects
Details
- ISSN :
- 2300732X
- Volume :
- 16
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Reproductive biology
- Accession number :
- edsair.doi.dedup.....864075fae0a787645f8f1eb017f92500