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Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study

Authors :
Lidia Daimiel
Jordi Salas-Salvadó
Francisco J. Tinahones
Olga Portolés
Blanca Riquelme-Gallego
Pilar Matía-Martín
Laura Compañ-Gabucio
Helmut Schröder
Ángel M. Alonso-Gómez
Josep Vidal
Clotilde Vázquez
J. Alfredo Martínez
F. Javier Barón López
Emilio Ros
Juan Carlos Benavente Marín
José Carlos Fernández-García
Ramon Estruch
Miguel Fiol
Xavier Pintó
Ana García-Arellano
Jadwiga Konieczna
José Lapetra
Josep A. Tur
Montserrat Fitó
Andrés Díaz-López
Laura Tomaino
Olga Castañer
Eva M. Asensio
Miguel Ángel Martínez-González
Aina M. Galmes-Panades
José Manuel Santos-Lozano
Itziar Abete
Luis Alfredo Mira-Castejón
Dora Romaguera
Cristina Razquin
Antonio Garcia-Rios
Karla Alejandra Pérez-Vega
Dolores Corella
Nerea Becerra-Tomás
Francisca Fiol
Jesús Vioque
Miguel Ruiz-Canela
Luis Serra-Majem
Veronica Varela-Mato
Ana Galera
Anai Moreno Rodríguez
Catalina M. Mascaró
Jessica Vaquero-Luna
Rosa Casas
José J. Gaforio
Christopher Papandreou
Julia Wärnberg
Rafael Manuel Micó Pérez
Source :
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, r-FISABIO: Repositorio Institucional de Producción Científica, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO), Dipòsit Digital de la UB, Universidad de Barcelona, The International Journal of Behavioral Nutrition and Physical Activity, r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante, instname, Dipòsit Digital de Documents de la UAB, Universitat Autònoma de Barcelona, International Journal of Behavioral Nutrition and Physical Activity, Vol 16, Iss 1, Pp 1-12 (2019), Dadun. Depósito Académico Digital de la Universidad de Navarra, Digibug. Repositorio Institucional de la Universidad de Granada, r-FISABIO. Repositorio Institucional de Producción Científica
Publication Year :
2019
Publisher :
Springer Science and Business Media LLC, 2019.

Abstract

Background: This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Methods: This is a cross-sectional analysis of baseline data from 2189 Caucasian men and women (age 55-75 years, BMI 27-40 Kg/m(2)) from the PREDIMED-Plus study (http://www.predimedplus.com/). All participants had >= 3 components of the metabolic syndrome. Inactive time, physical activity and time in bed were objectively determined using triaxial accelerometers GENEActiv during 7 days (ActivInsights Ltd., Kimbolton, United Kingdom). Multiple adjusted linear and logistic regression models were used. Isotemporal substitution regression modelling was performed to assess the relationship of replacing the amount of time spent in one activity for another, on each outcome, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Results: Inactive time was associated with indicators of obesity and the metabolic syndrome. Reallocating 30min per day of inactive time to 30 min per day of time in bed was associated with lower BMI, waist circumference and glycated hemoglobin (HbA1c) (all p-values < 0.05). Reallocating 30 min per day of inactive time with 30 min per day of LPA or MVPA was associated with lower BMI, waist circumference, total fat, visceral adipose tissue, HbA1c, glucose, triglycerides, and higher body muscle mass and HDL cholesterol (all p-values < 0.05). Conclusions: Inactive time was associated with a poor cardio-metabolic profile. Isotemporal substitution of inactive time with MVPA and LPA or time in bed could have beneficial impact on cardio-metabolic health.<br />The PREDIMED-Plus trial was supported by the official funding agency for biomedical research of the Spanish government, ISCIII through the Fondo de Investigacion para la Salud (FIS), which is co-funded by the European Regional Development Fund (four coordinated FIS projects led by Jordi Salas-Salvado and Josep Vidal, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926); the Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-PLUS grant to Jordi Salas-Salvado; the European Research Council grant (Advanced Research Grant 2013-2019; 340918) to Miguel Angel Martinez-Gonzalez; the Recercaixa grant to Jordi Salas-Salvado (2013ACUP00194); grants from the Consejeria de Salud de la Junta de Andalucia (PI0458/2013; PS0358/2016; PI0137/2018); the PROMETEO/2017/017 grant from the Generalitat Valenciana; Grant of support to research groups no. 35/2011 (Balearic Islands Gov. & FEDER funds) to Catalina M. Mascaro and Josep A. Tur; FPU Programme, PhD fellowship (Spanish Ministry of Science, Innovation & Universities) to Catalina M. Mascaro; the Astra Zeneca Young Investigators Award in Category of Obesity and Diabetes 2017 to Dora Romaguera; Juan de la Cierva-formacion research grant (FJCI-2015-24058) of the Spanish Ministry of Economy, Industry and Competitiveness and European Social Funds to Jadwiga Konieczna; the 'FOLIUM' programme within the FUTURMed project from the Fundacion Instituto de Investigacion Sanitaria Illes Balears (financed by 2017annual plan of the sustainable tourism tax and at 50% with charge to the ESF Operational Program 2014-2020 ofthe Balearic Islands) to Jadwiga Konieczna. JR17/00022 contract to Olga Castaner from ISCIII. CIBERobn (Centros de Investigacion Biomedica en Red: Obesidad y Nutricion), CIBEResp (Centros de Investigacion Biomedica en Red: Epidemiologia y Salud Publica) and CIBERdem (Centros de Investigacion Biomedica en Red: Diabetes y Enfermedades). None of the funding sources took part in the design, collection, analysis or interpretation of the data and in writing the manuscript, or in the decision to submit the manuscript for publication.

Subjects

Subjects :
Male
sueño
Time Factors
humanos
Medicine (miscellaneous)
ejercicio físico
Type 2 diabetes
030204 cardiovascular system & hematology
Logistic regression
triglicéridos
Isotemporal substitution
chemistry.chemical_compound
0302 clinical medicine
Risk Factors
Accelerometry
Inactive time
Moderate-to-vigorous physical activity
Moderate to vigorous physical activity
Time in bed
lcsh:RC620-627
mediana edad
Adiposity
Cardiometabolic risk, Inactive time, Isotemporal substitution, Light physical activity, Moderate to vigorous physical activity, Time in bed
Metabolic Syndrome
anciano
Nutrition and Dietetics
lcsh:Public aspects of medicine
colesterol
Middle Aged
Light physical activity
3. Good health
lcsh:Nutritional diseases. Deficiency diseases
Cholesterol
Cardiovascular diseases
Female
adiposidad
Waist Circumference
medicine.medical_specialty
Waist
Rest
Physical Therapy, Sports Therapy and Rehabilitation
Clinical nutrition
03 medical and health sciences
factores de tiempo
Ciencias de la Salud::Medicina preventiva [Materias Investigacion]
Internal medicine
acelerometría
Diabetes Mellitus
medicine
factores de riesgo
Humans
Obesity
obesidad
Exercise
Triglycerides
Aged
Retrospective Studies
perímetro abdominal
Malalties cardiovasculars
business.industry
Research
estudios retrospectivos
Cholesterol, HDL
lcsh:RA1-1270
030229 sport sciences
Physical fitness
medicine.disease
United Kingdom
Cardiometabolic risk
Cross-Sectional Studies
Blood pressure
Diabetes Mellitus, Type 2
chemistry
Descans
Glycated hemoglobin
Sedentary Behavior
Metabolic syndrome
Sleep
business
estudios transversales
Condició física

Details

ISSN :
14795868
Volume :
16
Database :
OpenAIRE
Journal :
International Journal of Behavioral Nutrition and Physical Activity
Accession number :
edsair.doi.dedup.....863b224e27149cb820c4728071b32695