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Supplementary Figure 2. Experiment that was used to select drug concentrations for combination screen. from An Unbiased Oncology Compound Screen to Identify Novel Combination Strategies

Authors :
Stuart D. Shumway
Andrew Bloecher
Theresa Zhang
Christopher Winter
Brian B. Haines
Razvan Cristescu
William Arthur
Andrey Loboda
Serguei Lejnine
Astrid Kral
Jing Li
Yaping Liu
Brian Roberts
Melissa Chenard
Igor Feldman
Yair Benita
Jennifer O'Neil
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

We ran 8 titration point curves (shown in gray) and then picked 4 concentration points that cover best the response curve for all cell lines (shown in red). The first point is the top plateau, the last is the bottom plateau and the other 2 are in between.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....862f8c6540eb40e57d14a4dea52aef8d