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Overcoming protein diversity on arrays
- Source :
- Nature methods. 3(12)
- Publication Year :
- 2006
-
Abstract
- Researchers show that to reliably establish protein interaction networks from microarray data it is necessary to measure saturation binding curves for each arrayed protein and its potential binding partners.
- Subjects :
- Genetics
Saturation binding
Microarray analysis techniques
Gene Expression Profiling
Measure (physics)
Protein Array Analysis
Reproducibility of Results
Cell Biology
Computational biology
Biology
Biochemistry
Sensitivity and Specificity
Protein Interaction Networks
Protein diversity
Protein Interaction Mapping
Artifacts
Molecular Biology
Algorithms
Biotechnology
Subjects
Details
- ISSN :
- 15487091
- Volume :
- 3
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Nature methods
- Accession number :
- edsair.doi.dedup.....85f5decd792f5c910450c8c2279ab75d