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CZE determination of somatostatin in pharmaceutical preparations

Authors :
Renata Jasionowska
M. Masci
F. Coccioli
G. P. Cartoni
Source :
Journal of Pharmaceutical and Biomedical Analysis. 23:143-146
Publication Year :
2000
Publisher :
Elsevier BV, 2000.

Abstract

We propose a simple and accurate method for CE quantitative determination of somatostatin in pharmaceutical preparations. The method is specific for somatostatin as indicated by the resolution between the analyte and the analogue peptides which differ from somatostatin by one aminoacid. The linearity range is from 0.02 to 0.35 mg/ml. The recovery of the somatostatin from a pharmaceutical product is about 100.0%.

Details

ISSN :
07317085
Volume :
23
Database :
OpenAIRE
Journal :
Journal of Pharmaceutical and Biomedical Analysis
Accession number :
edsair.doi.dedup.....85e10514d5e461cccd128549ea1553a2
Full Text :
https://doi.org/10.1016/s0731-7085(00)00284-3