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Associations of Maternal Weight Status Before, During, and After Pregnancy with Inflammatory Markers in Breast Milk
- Source :
- Obesity (Silver Spring), Obesity (Silver Spring, Md.)
- Publication Year :
- 2018
-
Abstract
- Objective To examine the associations of maternal weight status before, during, and after pregnancy with breast milk C-Reactive Protein (CRP) and Interleukin-6 (IL-6), two bioactive markers of inflammation, measured at one and three months postpartum. Methods Participants were 134 exclusively breastfeeding mother-infant dyads taking part in the Mothers and Infants LinKed for Health (MILK) study, who provided breast milk samples. Pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) were assessed by chart abstraction; postpartum weight loss was measured at the one and three month study visits. Linear regression was used to examine the associations of maternal weight status with repeated measures of breast milk CRP and IL-6 at one and three months, after adjustment for potential confounders. Results Pre-pregnancy BMI and excessive GWG, but not total GWG or postpartum weight loss, were independently associated with breast milk CRP after adjustment (β=0.49, p
- Subjects :
- 0301 basic medicine
Adult
Male
Endocrinology, Diabetes and Metabolism
Medicine (miscellaneous)
Physiology
Mothers
Breast milk
Weight Gain
Article
Cohort Studies
03 medical and health sciences
Young Adult
Endocrinology
Pregnancy
Medicine
Humans
Prospective Studies
Weight status
2. Zero hunger
030109 nutrition & dietetics
Nutrition and Dietetics
Milk, Human
business.industry
Interleukin-6
Postpartum Period
Infant
Middle Aged
medicine.disease
Obesity
3. Good health
maternal obesity
C-Reactive Protein
breast feeding
gestational weight gain
Female
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Obesity (Silver Spring), Obesity (Silver Spring, Md.)
- Accession number :
- edsair.doi.dedup.....85e0a373cead1d6b4721424c187893fc