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Neonatal haemochromatosis with reversible pituitary involvement
- Source :
- Transplant International. 27:e76-e79
- Publication Year :
- 2014
- Publisher :
- Frontiers Media SA, 2014.
-
Abstract
- Summary Neonatal haemochromatosis is a rare alloimmune gestational disease with a high mortality. The hallmark of neonatal haemochromatosis is severe neonatal liver failure associated with extrahepatic siderosis. Thus far, no pituitary dysfunction has been reported to result from the tissue damage associated with extrahepatic siderosis. The present report describes a neonate with neonatal haemochromatosis and secondary hypothyroidism associated with pituitary iron deposition. Both the conditions were successfully treated by ABO-incompatible liver transplantation. Pituitary gland dysfunction is another possible extrahepatic manifestation of neonatal haemochromatosis, and it is reversible after liver transplantation.
- Subjects :
- Male
Pathology
medicine.medical_specialty
Pituitary gland
Pituitary Diseases
medicine.medical_treatment
Iron deposition
Hypopituitarism
Disease
Liver transplantation
ABO Blood-Group System
neonatal haemochromatosis
medicine
Neonatal hemochromatosis
Humans
ABO-incompatible liver transplantation
Transplantation
business.industry
Infant, Newborn
medicine.disease
Liver Transplantation
medicine.anatomical_structure
hypopituitarism
Blood Group Incompatibility
Gestation
Hemochromatosis
hypothyroidism
Siderosis
business
Subjects
Details
- ISSN :
- 09340874
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Transplant International
- Accession number :
- edsair.doi.dedup.....85dd4164e539df8d4d5dd68957a3d822