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Antibiotics in treatment of peritonsillar infection: clindamycin versus penicillin
- Source :
- The Journal of Laryngology & Otology. 135:64-69
- Publication Year :
- 2021
- Publisher :
- Cambridge University Press (CUP), 2021.
-
Abstract
- ObjectiveThis study aimed to compare antibiotic treatment with clindamycin versus penicillin V or G in terms of time to recovery and recurrence in patients with peritonsillar infection, including both peritonsillar cellulitis and peritonsillar abscess.MethodThis retrospective cohort study examined the records of 296 patients diagnosed with peritonsillar infection. Based on the ENT doctor's choice of antibiotics, patients were divided into clindamycin and penicillin groups.ResultsMean number of days in follow up was 3.5 days in the clindamycin group and 3.4 days in the penicillin group. The recurrence rate within 2 months was 7 per cent in the clindamycin group and 4 per cent in the penicillin group.ConclusionThis study found no significant differences in either recovery or recurrence between the groups. This supports the use of penicillin as a first-line treatment, considering the greater frequency of adverse effects of clindamycin shown in previous studies, as well as its profound collateral damage on the intestinal microbiota, resulting in antibiotic resistance.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
medicine.drug_class
Antibiotics
Penicillins
Cohort Studies
Young Adult
03 medical and health sciences
0302 clinical medicine
Antibiotic resistance
Recurrence
Internal medicine
medicine
Humans
In patient
Peritonsillar Abscess
Child
030223 otorhinolaryngology
Adverse effect
Aged
Retrospective Studies
Aged, 80 and over
0303 health sciences
030306 microbiology
business.industry
Clindamycin
Cellulitis
Retrospective cohort study
General Medicine
Middle Aged
Anti-Bacterial Agents
Penicillin
Tonsillitis
Treatment Outcome
Otorhinolaryngology
Female
business
medicine.drug
Subjects
Details
- ISSN :
- 17485460 and 00222151
- Volume :
- 135
- Database :
- OpenAIRE
- Journal :
- The Journal of Laryngology & Otology
- Accession number :
- edsair.doi.dedup.....85ce9b0144e9a48f0d8a5d919e5f71c7