Back to Search Start Over

Involvement of a Phage-Encoded Wzy Protein in the Polymerization of K127 Units To Form the Capsular Polysaccharide of Acinetobacter baumannii Isolate 36-1454

Authors :
Nikolay P. Arbatsky
Anastasiya A. Kasimova
Alexander S. Shashkov
Mikhail M. Shneider
Anastasiya V. Popova
Dmitry A. Shagin
Andrey A. Shelenkov
Yuliya V. Mikhailova
Yurii G. Yanushevich
Ruth M. Hall
Yuriy A. Knirel
Johanna J. Kenyon
Source :
Microbiology Spectrum. 10
Publication Year :
2022
Publisher :
American Society for Microbiology, 2022.

Abstract

Bacteriophage therapy is an attractive innovative treatment for infections caused by extensively drug resistant Acinetobacter baumannii , for which there are few effective antibiotic treatments remaining. Capsular polysaccharide (CPS) is a primary receptor for many lytic bacteriophages, and thus knowledge of the chemical structures of CPS produced by the species will underpin the identification of suitable phages for therapeutic cocktails.

Details

ISSN :
21650497
Volume :
10
Database :
OpenAIRE
Journal :
Microbiology Spectrum
Accession number :
edsair.doi.dedup.....85a351491266b0fcde81e2fe912bba69