Back to Search
Start Over
Transposable Elements (Human Endogenous Retroviruses) in Cancer
- Source :
- Critical Reviews in Eukaryotic Gene Expression. 27:219-227
- Publication Year :
- 2017
- Publisher :
- Begell House, 2017.
-
Abstract
- Transposable elements (TEs) have shown a great significance in regulatory elements research, being responsible for different types of cancers. They are divided into three classes on the basis of their mode of transposition, structural properties, and their homology with DNA sequence. In evaluating their role in cancers and other pathologies, researchers have found extensive evidence of their involvement. TEs can also be used as genetic markers for cancers and help in identifying potential therapeutic targets. There have been advancements in the management of hepatocellular carcinoma using TEs as regulatory components involved in the cancer's pathogenesis.
- Subjects :
- 0301 basic medicine
Transposable element
Carcinoma, Hepatocellular
Carcinogenesis
Human endogenous retrovirus
Endogenous Retroviruses
Liver Neoplasms
food and beverages
Endogenous retrovirus
Computational biology
Biology
Homology (biology)
DNA sequencing
03 medical and health sciences
030104 developmental biology
Genetic marker
DNA Transposable Elements
Genetics
Humans
Molecular Biology
Subjects
Details
- ISSN :
- 10454403
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Critical Reviews in Eukaryotic Gene Expression
- Accession number :
- edsair.doi.dedup.....859dc1c589a760327aed087d47a3dbf0