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Exercise Training for Pulmonary Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Source :
- Biological Research For Nursing. 23:442-454
- Publication Year :
- 2020
- Publisher :
- SAGE Publications, 2020.
-
Abstract
- Background:Pulmonary hypertension (PH) is a chronic disease with a notable health burden; regular exercise may improve specific health outcome measures.Objective:The objective of this meta-analysis was to estimate the effectiveness of exercise training for PH patients.Data sources:PubMed, CINAHL, SportDiscuss and Google Scholar databases and reference lists of included studies were searched.Study selection:The selection criteria were randomized controlled trials (RCTs) employing an exercise training intervention. Data were extracted from the entered studies for analysis. The primary outcomes were peak oxygen uptake (VO2peak), anaerobic threshold (AT), 6-minute walk distance (6-MWD), and quality of life (QoL) measures (physical component score and mental component score). The analysis included 9 articles with a total of 302 participants: intervention (n = 154), and control (n = 148).Results:In the pooled analysis, improvements were seen in: VO2peak, mean difference (MD) 2.79 ml/kg/min (95% CI 2.00 to 3.59, p < 0.00001); AT, MD 107.83 ml/min (95% CI 39.64 to 176.00, p = 0.002); and 6-MWD, MD 46.67 meters (95% CI 32.39 to 60.96, p < 0.00001). Differences were found in the SF-36 physical component score MD 3.57 (95% CI 2.04 to 5.10, p < 0.00001) and the SF-36 mental component score MD 3.92 (95% CI 1.92 to 5.91, p = 0.001).Conclusion:This meta-analysis demonstrates exercise training has a beneficial effect on fitness, walking performance, and self-reported QoL in PH patients.
- Subjects :
- medicine.medical_specialty
Hypertension, Pulmonary
030204 cardiovascular system & hematology
Health outcomes
law.invention
03 medical and health sciences
0302 clinical medicine
Quality of life (healthcare)
Randomized controlled trial
Regular exercise
law
medicine
Humans
Exercise
Randomized Controlled Trials as Topic
Research and Theory
business.industry
Exercise capacity
medicine.disease
Pulmonary hypertension
Exercise Therapy
Chronic disease
030228 respiratory system
Meta-analysis
Quality of Life
Physical therapy
business
Subjects
Details
- ISSN :
- 15524175 and 10998004
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Biological Research For Nursing
- Accession number :
- edsair.doi.dedup.....85968409aa52672e22981cb30d2e35e4