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Comparison of immune parameters of sheep with naturally high or low plasma concentrations of melatonin
- Source :
- Journal of Pineal Research. 31:248-255
- Publication Year :
- 2001
- Publisher :
- Wiley, 2001.
-
Abstract
- Studies in rodents and humans have suggested that the pineal gland and its secretory product melatonin play an important role in the modulation of the immune system. In this study, we tested the hypothesis of a difference in immune parameters between ewes with naturally high vs. low circulating melatonin. Thus, two comparable groups of 10 Ile-de-France sheep were selected from a large flock, for their naturally high and low plasma concentrations of melatonin. The mean plasma melatonin concentrations during daytime (09:00 hr) and nighttime (24:00 hr) were, respectively, 9 and 664 pg/mL (high group) and 5 and 169 pg/mL (low group; P
- Subjects :
- medicine.medical_specialty
Stimulation
Lymphocyte Activation
Melatonin
Leukocyte Count
Pineal gland
Endocrinology
Immune system
Internal medicine
medicine
Animals
Immunity, Cellular
Sheep
biology
In vitro
medicine.anatomical_structure
Immunization
Immune System
Antibody Formation
biology.protein
Female
Flock
Antibody
medicine.drug
Subjects
Details
- ISSN :
- 1600079X and 07423098
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Journal of Pineal Research
- Accession number :
- edsair.doi.dedup.....84c308a0f7e11e201e4a487ed9067090