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Correction to: In vivo imaging of early stages of rheumatoid arthritis by α5β1-integrin-targeted positron emission tomography

Authors :
Johannes Notni
Florian T. Gassert
Katja Steiger
Wilko Weichert
Markus Schwaiger
Peter Sommer
Horst Kessler
Reinhard Meier
Melanie A. Kimm
Ernst J. Rummeny
Source :
EJNMMI Research, Vol 9, Iss 1, Pp 1-1 (2019)
Publication Year :
2019
Publisher :
Springer Science and Business Media LLC, 2019.

Abstract

Following publication of the original article [1], the authors have reported an error in the ‘Histopathology’ (under ‘Materials and methods’) section of the article that compromises the reproducibility of the paper. Namely, they have advised that the procedure for α5 integrin immunohistochemistry has not been reported correctly. Unlike described in the paper, α5 IHC has been performed as follows: “For alpha 5 integrin immunohistochemistry, a rabbit polyclonal antibody (LSBio, LS-B6179, diluted 1:7.500) was used. Immunohistochemistry was performed on a Leica BondRXm system (Leica, Wetzlar, Germany) using deparaffinization solution, pretreated with Epitope retrieval solution 2 (corresponding to EDTA buffer pH8) for 30 minutes. Antibody binding was detected with a polymer refine detection kit without post primary reagent and visualized with DAB as a dark brown precipitate.” The authors apologize for this error. CA extern

Details

ISSN :
2191219X
Volume :
9
Database :
OpenAIRE
Journal :
EJNMMI Research
Accession number :
edsair.doi.dedup.....84c1d180b0cf6205508fdd45acbeaa09
Full Text :
https://doi.org/10.1186/s13550-019-0582-x