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Lunasin in wheat: a chemical and molecular study on its presence or absence
- Publication Year :
- 2014
-
Abstract
- Lunasin is a peptide whose anticancer properties are widely reported. Originally isolated from soybean seeds, lunasin was also found in cereal (wheat, rye, barley and Triticale), Solanum and amaranthus seeds. However, it was recently reported that searches of transcript and DNA sequence databases for wheat and other cereals failed to identify sequences with similarity to those encoding the lunasin peptide in soy. In order to clarify the presence or absence of lunasin in wheat varieties, a broad investigation based on chemical (LC-ESI-MS) and molecular (PCR) analyses was conducted. Both approaches pointed out the absence of lunasin in the investigated wheat genotypes; in particular no compounds with a molecular weight similar to that of lunasin standard and no lunasin-related sequences were found in the analysed wheat samples. These findings confirm the hypothesis, reported in recent researches, that lunasin is not a wheat-derived peptide.
- Subjects :
- DNA, Plant
Genotype
030309 nutrition & dietetics
Peptide
Biology
Lunasin
Analytical Chemistry
03 medical and health sciences
0404 agricultural biotechnology
Botany
Cereal
Triticum
Plant Proteins
2. Zero hunger
chemistry.chemical_classification
0303 health sciences
food and beverages
04 agricultural and veterinary sciences
General Medicine
Sequence Analysis, DNA
Triticale
biology.organism_classification
BIOACTIVE PEPTIDES
040401 food science
3. Good health
Molecular Weight
Biochemistry
chemistry
DNA Sequence Databases
Seeds
Wheat
Soybean Proteins
Soybeans
Solanum
Food Science
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....848f7c2909c6128f3d8fb0a3e845cb87