Additional file 1 of Osteophytes mediate the associations between cartilage morphology and changes in knee symptoms in patients with knee osteoarthritis

Additional file 1: Table S1. Mediation by osteophytes on the associations between total cartilage defects and changes in knee symptoms in vitamin D supplement group. Table S2. Mediation by osteophytes on the associations between total cartilage defects and changes in knee symptoms in placebo group. Table S3. Mediation by osteophytes on the associations between total cartilage volumes and changes in knee symptoms in vitamin D supplement group. Table S4. Mediation by osteophytes on the associations between total cartilage volumes and changes in knee symptoms in placebo group. Table S5. Baseline characteristics of participants who completed the study vs loss to follow-up. Table S6. Mediation by osteophytes on the associations between total cartilage defects and changes in the knee symptoms in males. Table S7. Mediation by osteophytes on the associations between total cartilage defects and changes in knee symptoms in females. Table S8. Mediation by osteophytes on the associations between total cartilage volumes and changes in knee symptoms in males. Table S9. Mediation by osteophytes on the associations between total cartilage volumes and changes in knee symptoms in females. Table S10. Mediation by follow-up osteophytes on the associations between baseline total cartilage defects and changes in knee symptoms. Table S11. Mediation by follow-up osteophytes on the associations between baseline total cartilage volume and changes in knee symptoms.