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Vitamin D regulates insulin and ameliorates apoptosis and oxidative stress in pancreatic tissues of rats with streptozotocin-induced diabetes

Authors :
Fatima El Zahra M. Fathi
Kadry M. Sadek
Asmaa F. Khafaga
Abdel Wahab Al senosy
Hanan A. Ghoniem
Sahar Fayez
Mohamed F. Zeweil
Source :
Environmental Science and Pollution Research. 29:90219-90229
Publication Year :
2022
Publisher :
Springer Science and Business Media LLC, 2022.

Abstract

This study was designed to evaluate the potential therapeutic efficacy of vitamin D (Vit D) in averting the harmful effects of type 2 diabetes mellitus (T2D). Forty male Wistar rats were allotted into four groups: (1) the control, (2) Vit D, (3) streptozotocin (STZ), and (4) STZ + Vit D groups. Rats co-treated with Vit D had significantly (p p p

Details

ISSN :
16147499 and 09441344
Volume :
29
Database :
OpenAIRE
Journal :
Environmental Science and Pollution Research
Accession number :
edsair.doi.dedup.....845642a48d1a44463fc65f5d66a3575e
Full Text :
https://doi.org/10.1007/s11356-022-22064-2