The surgical management of oral and maxillofacial manifestations of Gardner syndrome

Gardner syndrome (GS) is a rare autosomal-dominant genetic disorder characterized by multiple colorectal adenomatous polyps and extraintestinal lesions, such as multiple osteomas, dental abnormalities, polyps of the stomach and small bowel, and mesenchymal tumors of the skin and soft tissues. Although most cases show familial clustering, about 30% of cases occur because of a new dominant mutation. 1-4