Back to Search
Start Over
Effects of high-fat diets on inflammation and antioxidant status in rats : comparison between palm olein and olive oil
- Source :
- Acta Biochimica Polonica, Acta Biochimica Polonica, 2021, 68 (4), pp.739-744. ⟨10.18388/abp.2020_5639⟩, Acta Biochimica Polonica, Acta Biochimica Polonica, In press, 68 (4), pp.739-744. ⟨10.18388/abp.2020_5639⟩, Acta Biochimica Polonica, Acta Biochimica Polonica, In press, ⟨10.18388/abp.2020_5639⟩
- Publication Year :
- 2021
- Publisher :
- Polskie Towarzystwo Biochemiczne (Polish Biochemical Society), 2021.
-
Abstract
- Palm olein (PO) and olive oil (OO) are widely consumed in the world. PO is considered harmful to health, whereas OO is considered healthy. The aim of the study was to compare the effects of consumption of these oils on antioxidant status and inflammation in rats. This was an experimental study in male wistar rats fed a diet containing 30% of each oil. Rats had free access to food and water. After being fed for 12 weeks, animals were sacrificed and liver and aortic blood were collected. Plasma was used for the determination of interleukin-6 (IL-6) and oxidative stress parameters (Superoxide dismutase -SOD; Gluthation peroxidase - GPx; Thiobarbituric acid reactive substances - TBARS; Thiol groups and isoprostane). The inflammation and oxidative stress status as well as the expression of several genes/proteins were also analyzed in liver homogenate. No significant differences were observed between PO and OO in plasma and liver levels of the studied inflammation and oxidative stress parameters. This study showed that the consumption of PO induces an antioxidant status superimposable to that of OO. Key words : Palm olein - Olive oil - Oxidative stress - Inflammation - High fat diet
- Subjects :
- Male
Antioxidant
Isoprostane
Thiobarbituric acid
medicine.medical_treatment
Inflammation
Palm Oil
Diet, High-Fat
medicine.disease_cause
Antioxidants
General Biochemistry, Genetics and Molecular Biology
Superoxide dismutase
03 medical and health sciences
chemistry.chemical_compound
palm olein
medicine
TBARS
Animals
oxidative stress
Food science
Rats, Wistar
[SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism
0303 health sciences
biology
high fat diet
030302 biochemistry & molecular biology
[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism
olive oil
Rats
[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition
Liver
chemistry
inflammation
biology.protein
medicine.symptom
[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
Oxidative stress
Peroxidase
Subjects
Details
- ISSN :
- 1734154X and 0001527X
- Database :
- OpenAIRE
- Journal :
- Acta Biochimica Polonica
- Accession number :
- edsair.doi.dedup.....842bcd36dcfc00f053792167b5cac5d5