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What can be learned from the history of recurrence in migraine? A comment
- Source :
- The Journal of Headache and Pain
- Publication Year :
- 2009
- Publisher :
- Springer Science and Business Media LLC, 2009.
-
Abstract
- Recurrence was first recognised as a clinical problem in 1989 with the advent of sumatriptan. The history of recurrence in early sumatriptan randomised clinical trials is described. Recurrence has been ascribed to patient-dependent factors but experience with ergot alkaloids suggested that recurrence can also be treatment-dependent. Possible mechanisms for recurrence are discussed.
- Subjects :
- medicine.medical_specialty
Neurology
Migraine Disorders
Clinical Neurology
Review Article
Neurological disorder
Triptans
Recurrence
Ergotamine
medicine
Humans
Vasoconstrictor Agents
Clinical Trials as Topic
Sumatriptan
Vascular disease
business.industry
General surgery
General Medicine
musculoskeletal system
medicine.disease
Surgery
Clinical trial
Anesthesiology and Pain Medicine
Migraine
cardiovascular system
Neurology (clinical)
business
medicine.drug
Subjects
Details
- ISSN :
- 11292377 and 11292369
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- The Journal of Headache and Pain
- Accession number :
- edsair.doi.dedup.....84007ec702112efa07e97261ccd10d41