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Capillaroscopy: a useful tool in the early diagnosis of connective tissue disease and non-scleroderma spectrum disorders
- Source :
- Minerva Cardiology and Angiology. 70
- Publication Year :
- 2022
- Publisher :
- Edizioni Minerva Medica, 2022.
-
Abstract
- BACKGROUND Detection of early capillaroscopic alterations in the preclinical phase may prove useful in patients with non-scleroderma connective tissue disease (CTD). We aimed to verify whether certain capillaroscopic alterations, alone or in combination, might be predictive of CTD. METHODS We retrospectively collected data on patients with Raynaud's phenomenon who underwent capillaroscopy conducted by highly expert examiners with a degree in vascular medicine at our institutions. Included subjects were divided in two groups: those developing rheumatic disease during follow-up, and those without subsequent diagnosis of CTD. Notably, we excluded subjects who presented with an evident scleroderma pattern or rheumatic disease during their initial examination. RESULTS We included a total of 76 patients, 60 who developed CTD during follow-up, which spanned in this group 23±7 months, and 16 who did not develop CTD during follow-up, which spanned 23±9 months. The following features were significantly associated with Raynaud's phenomenon: 1) angiotectonic disorder (p
- Subjects :
- medicine.medical_specialty
business.industry
Rheumatic disease
Raynaud Disease
medicine.disease
Dermatology
Connective tissue disease
Scleroderma
Microscopic Angioscopy
Scleroderma, Localized
Early Diagnosis
Preclinical phase
Rheumatic Diseases
Ectasia
Humans
Medicine
In patient
CTD
Connective Tissue Diseases
Cardiology and Cardiovascular Medicine
business
Pathological
Retrospective Studies
Subjects
Details
- ISSN :
- 27245772 and 27245683
- Volume :
- 70
- Database :
- OpenAIRE
- Journal :
- Minerva Cardiology and Angiology
- Accession number :
- edsair.doi.dedup.....83f9f877f5205b380f7ffa671c9cae33