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Correction to 'Synergistic Inhibition of SARS-CoV-2 Replication Using Disulfiram/Ebselen and Remdesivir'

Authors :
Carmay Lim
Ting Chen
Yi-Ping Chen
Chun-Ping Chang
Karen Sargsyan
Cheng-Yin Fei
Yi-Ling Lin
Chun-Che Liao
Hanna S. Yuan
Jian-Jong Liang
Source :
ACS Pharmacology & Translational Science
Publication Year :
2021
Publisher :
American Chemical Society, 2021.

Abstract

The SARS-CoV-2 replication and transcription complex (RTC) comprising nonstructural protein (nsp) 2-16 plays crucial roles in viral replication, reducing the efficacy of broad-spectrum nucleoside analog drugs such as remdesivir and evading innate immune responses. Most studies target a specific viral component of the RTC such as the main protease or the RNA-dependent RNA polymerase. In contrast, our strategy is to target

Details

Language :
English
ISSN :
25759108
Volume :
4
Issue :
3
Database :
OpenAIRE
Journal :
ACS Pharmacology & Translational Science
Accession number :
edsair.doi.dedup.....83ed2b416edaa0ad381e925d768385f4