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Malignant hyperthermia and althesin
- Source :
- Canadian Anaesthetists’ Society Journal. 24:514-521
- Publication Year :
- 1977
- Publisher :
- Springer Science and Business Media LLC, 1977.
-
Abstract
- General anaesthesia with Althesin was administered on two occasions to a patient who was identified as susceptible to malignant hyperthermia, in whom there was identified familial subclinical myopathy and once in another patient suffering from arthrogryposis multiplex congenita with a history of fever associated with two previous anaesthetics. In the first patient halothane was administered by accident in association with the Althesin, but no hyperpyrexia occurred. In the second instance nitrous oxide-oxygen and halothane were associated purposely with Althesin. In none of these cases was there any rise in temperature, muscle rigor or elevation of the serum CPK level. This experience corroborates the experimental evidence of Hall, et al.10 and Harrison, who reported that Althesin prevented the onset of hyperthermia, and the clinical reports of Page and Judelman. Althesin can be assumed to be an effective anaesthetic for malignant hyperthermia susceptible patients.
- Subjects :
- Male
Hyperthermia
medicine.medical_specialty
Pregnanediones
Anesthesiology
medicine
Humans
Anesthesia
General anaesthesia
Femur
Child
Myopathy
Subclinical infection
Arthrogryposis
Arthrogryposis multiplex congenita
business.industry
Malignant hyperthermia
General Medicine
medicine.disease
Surgery
Cleft Palate
Anesthesiology and Pain Medicine
Alfaxalone Alfadolone Mixture
Child, Preschool
Female
medicine.symptom
Halothane
Malignant Hyperthermia
business
medicine.drug
Subjects
Details
- ISSN :
- 14968975 and 00082856
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Canadian Anaesthetists’ Society Journal
- Accession number :
- edsair.doi.dedup.....83e611beed25a7a76e150a3883471551