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MRI-based comprehensive analysis of vascular anatomy and hemodynamics
- Source :
- Cardiovascular diagnosis and therapy, vol 11, iss 6, Cardiovasc Diagn Ther
- Publication Year :
- 2021
- Publisher :
- eScholarship, University of California, 2021.
-
Abstract
- BACKGROUND: Standardized methods for mapping the complex blood flow in vessels are essential for processing the large data volume acquired from 4D Flow MRI. We present a method for systematic and efficient analysis of anatomy and flow in large human blood vessels. To attain the best outcomes in cardiac surgery, vascular modifications that lead to secondary flow patterns such as vortices should be avoided. In this work, attention was paid to the undesired cancelation of vortices with opposite directions of rotation, known as Dean flow patterns, using hemodynamic parameters such as circulation and helicity density. METHODS: Our approach is based on the multiplanar reconstruction (MPR) of a multi-dimensional feature-space along the blood vessel’s centerline. Hemodynamic parameters and anatomic information were determined in-plane from the reconstructed feature-space and from the blood vessel’s centerline. A modified calculation of circulation and helicity density and novel parameters for quantifying Dean flow were developed. To test the model performance, we applied our methods to three test cases. RESULTS: Comprehensive information on position, magnitude and interrelation of vascular anatomy and hemodynamics were extracted from 4D Flow MRI datasets. The results show that the Dean flow patterns can be efficiently assessed using the novel parameters. CONCLUSIONS: Our approach to comprehensively and simultaneously quantify multiple parameters of vascular anatomy and hemodynamics from 4D Flow MRI provides new insights to map complex hemodynamic conditions.
- Subjects :
- Vascular anatomy
business.industry
Respiratory System
Hemodynamics
Bioengineering
Anatomy
fluid dynamics
Cardiorespiratory Medicine and Haematology
cardiovascular hemodynamics
Cardiovascular
4D Flow MRI
congenital heart disease
Original Article on Current Management Aspects in Adult Congenital Heart Disease (ACHD): Part IV
Medicine
Biomedical Imaging
Cardiology and Cardiovascular Medicine
business
4DPC-MRI
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Cardiovascular diagnosis and therapy, vol 11, iss 6, Cardiovasc Diagn Ther
- Accession number :
- edsair.doi.dedup.....83de9c80696c0527ce9f0ce2782ef130