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Real-world progression-free survival in first-line advanced non-small cell lung cancer treated with immunotherapy-based regimens using a US dataset
- Source :
- Data in Brief, Data in Brief, Vol 37, Iss, Pp 107195-(2021)
- Publication Year :
- 2021
- Publisher :
- Elsevier, 2021.
-
Abstract
- While results from clinical trials are important in determining the efficacy of treatment, restrictive eligibility criteria may limit generalizability to patient populations in the real-world setting. Real-world analyses can therefore identify subgroups of patients who may respond differently to specific therapeutic regimens. This supplementary data is supportive to the research article entitled “Real-world outcomes of immunotherapy–based regimens in first-line advanced non-small cell lung cancer” [1] . Using electronic health records data from a large demographically and geographically diverse oncology database, we present real-world progression-free survival (rwPFS) outcomes for patients with advanced non-small cell lung cancer in the United States treated with either first-line immunotherapy as monotherapy or single-agent immunotherapy combined with chemotherapy. rwPFS was estimated for patients in each treatment group using Kaplan-Meier methods; analyses were conducted separately for patients with squamous and non-squamous histology and stratified by Eastern Cooperative Oncology Group performance status, tumor programmed death ligand-1 expression, and presence of brain metastases.
- Subjects :
- Oncology
medicine.medical_specialty
Science (General)
First line
medicine.medical_treatment
Computer applications to medicine. Medical informatics
R858-859.7
03 medical and health sciences
Q1-390
Immune checkpoint inhibitors
0302 clinical medicine
Non-small cell lung cancer
Internal medicine
medicine
Research article
Real-world outcomes
Progression-free survival
Lung cancer
030304 developmental biology
Data Article
0303 health sciences
Chemotherapy
Multidisciplinary
business.industry
Immunotherapy
medicine.disease
Clinical trial
Non small cell
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 23523409
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Data in Brief
- Accession number :
- edsair.doi.dedup.....837df714f550057cdf5e73111c8687eb